Published in Nature Cell Biology 2017;19:79-81. Under misfolded protein stress, the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to restore homeostasis, or commits the cell to apoptosis. A study now uncovers how the UPR is governed by the circadian clock to adjust ER protein-folding...
News on our research published in Nature Cell Biology 2017;19:94-105 "Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress", by Carlos Maillo, Judit Martín, David Sebastián, Maribel Hernández-Alvarez, Mar García-Rocha, Oscar Reina, Antonio Zorzano, Mercedes Fernandez & Raúl Méndez. Co-corresponding authors:...
Published in Nature Cell Biology 2017;19:94-105 "Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress", by Carlos Maillo, Judit Martín, David Sebastián, Maribel Hernández-Alvarez, Mar García-Rocha, Oscar Reina, Antonio Zorzano, Mercedes Fernandez & Raúl Méndez. Co-corresponding authors: Raúl Méndez and Mercedes...
Presentation of the 2017 Research Grant Programme of the Scientific Foundation of the Spanish Association Against Cancer (AECC), by doctors Isabel Orbe, Nieves Mijimolle, Francesc Cardellach, Albert Biete and Mercedes Fernandez. November 29th, 2016. Place: Aula Magna, Faculty of Medicine, University of Barcelona Dr. Isabel Orbe, Director of the Scientific...
Amazing conferences on the most recent breakthroughs in cancer and new collaborations with world-leading experts!! This B-Debate, organized by IRB Barcelona scientists Raúl Méndez, Salvador Aznar-Benitah and Eduard Batlle, with Biocat and "la Caixa" Foundation, has gathered international experts in the fields of RNA processing and...
Excellent Barcelona BioMed Conference! (October 3-5, 2016) Many features of the development and physiology of living organisms are made possible by the plasticity of epithelial cells. Not only does it enable their transformation to different cell types, which is often reversible, it also facilitates their migration to...
Launch of a global movement for cancer research. The World Cancer Research Day gives us the opportunity to raise awareness and commit to the progress of cancer research as the only way to restrain the disease and improve patient survival rates and quality of life....
We thank Kimberly Brown (Henry Ford Hospital, Detroit), Bruce Bacon (Saint Louis University), and K. Rajender Reddy (University of Pennsylvania) for the invitation to write this article. "Pathogenesis of portal hypertension: Extrahepatic mechanisms" by Mercedes Fernandez, Marc Mejias, Ester Garcia-Pras, Javier Gallego, Nuria Pell, Marta Ramirez,...
Since our manuscript went on line it's had a bit of press coverage...
Published in Gastroenterology (2016) 150:982-997 "Sequential functions of CPEB1 and CPEB4 regulate pathologic expression of VEGF and angiogenesis in chronic liver disease", by Vittorio Calderone, Javier Gallego, Gonzalo Fernandez-Miranda, Ester Garcia-Pras, Carlos Maillo, Annalisa Berzigotti, Marc Mejias, Felice Alessio Bava, Ana Angulo-Urarte, Mariona Graupera, Pilar Navarro, Jaime...
We gratefully appreciate their support!...
Mercedes Fernandez gave an invited lecture about chronic liver disease at the Volunteers Training Day of the Spanish Association Against Cancer (AECC) Read More ...
We gratefully appreciate their support! Read More ...
The Scientific Foundation of the Spanish Association Againts Cancer (AECC) has granted 1.2 million euros to our Coordinate Group (Mercedes Fernandez, Raul Mendez and Jordi Bruix). We gratefully appreciate their support! ...