Welcome message: Cells composing the liver microvasculature play essential roles in the pathophysiology of liver diseases, and therefore their study at the bench-side results essential to understand disease biology and to develop new therapeutics. The 2018 Basic School of Hepatology will provide updated information about how...
Invited Editorial, by Mercedes Fernandez, published in Hepatology 2018. Devoted to the study by Raevens et al. Placental growth factor inhibition targets pulmonary angiogenesis and represents a novel therapy for hepatopulmonary syndrome in mice. Hepatology. 2017 Oct 10. doi: 10.1002/hep.29579....
News on our research published in Scientific Reports 2017. “Therapeutic siRNA targeting endothelial KDR decreases portosystemic collateralization in portal hypertension”, by Javier Gallego*, Ester Garcia-Pras*, Marc Mejias, Nuria Pell, Ute Schaeper and Mercedes Fernandez (*co-first authors). Corresponding author: Mercedes Fernandez. Scientific Reports 2017, 7:14791 Link to Article. AECC Más Información...
News on our research published in Scientific Reports 2017. “Therapeutic siRNA targeting endothelial KDR decreases portosystemic collateralization in portal hypertension”, by Javier Gallego*, Ester Garcia-Pras*, Marc Mejias, Nuria Pell, Ute Schaeper and Mercedes Fernandez (*co-first authors). Corresponding author: Mercedes Fernandez. Scientific Reports 2017, 7:14791. Link to Article. More Information...
Published in Scientific Reports 2017. "Therapeutic siRNA targeting endothelial KDR decreases portosystemic collateralization in portal hypertension", by Javier Gallego*, Ester Garcia-Pras*, Marc Mejias, Nuria Pell, Ute Schaeper and Mercedes Fernandez (*co-first authors). Corresponding author: Mercedes Fernandez. Scientific Reports 2017;7:14791. https://www.ncbi.nlm.nih.gov/pubmed/29093528 Published in Abstract form in Hepatology 2017: "Gene therapy...
The Basic Science Young Investigator Travel Award of the American Association for the Study of Liver Disease (AASLD) recognizes outstanding young basic science researchers working on liver disease. Nuria presented our research in a Parallel Session at the 68th Annual Meeting of the AASLD (Washington DC, October 23, 2017). Congratulations!! Published...
News on our research published in Gut 2017;66:1306-1320 "Role and therapeutic potential of vascular stem/progenitor cells in pathological neovascularisation during chronic portal hypertension", by Ester Garcia-Pras, Javier Gallego, Laura Coch, Marc Mejias, Gonzalo Fernandez-Miranda, Ricardo Pardal, Jaime Bosch, Raul Mendez and Mercedes Fernandez. Corresponding author: Mercedes Fernandez Jano IDIBAPS CIBEREHD Clinic GacetaMedica Agencia Sinc...
Published in Gut 2017;66:1306-1320 "Role and therapeutic potential of vascular stem/progenitor cells in pathological neovascularisation during chronic portal hypertension", by Ester Garcia-Pras, Javier Gallego, Laura Coch, Marc Mejias, Gonzalo Fernandez-Miranda, Ricardo Pardal, Jaime Bosch, Raul Mendez and Mercedes Fernandez Corresponding author: Mercedes Fernandez Read More ...
We thank Pablo Muriel (CINVESTAV-IPN, Mexico), for the invitation to write this Review. "Gastroesophageal Varices", by Mercedes Fernandez and Juan G Abraldes. Corresponding author: Mercedes Fernandez. Published in: Liver Pathophysiology: Therapies & Antioxidants (2017), Academic Press, Elsevier. ...
Published in Nature Cell Biology 2017;19:79-81. Under misfolded protein stress, the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to restore homeostasis, or commits the cell to apoptosis. A study now uncovers how the UPR is governed by the circadian clock to adjust ER protein-folding...
News on our research published in Nature Cell Biology 2017;19:94-105 "Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress", by Carlos Maillo, Judit Martín, David Sebastián, Maribel Hernández-Alvarez, Mar García-Rocha, Oscar Reina, Antonio Zorzano, Mercedes Fernandez & Raúl Méndez. Co-corresponding authors:...
Published in Nature Cell Biology 2017;19:94-105 "Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress", by Carlos Maillo, Judit Martín, David Sebastián, Maribel Hernández-Alvarez, Mar García-Rocha, Oscar Reina, Antonio Zorzano, Mercedes Fernandez & Raúl Méndez. Co-corresponding authors: Raúl Méndez and Mercedes...
Presentation of the 2017 Research Grant Programme of the Scientific Foundation of the Spanish Association Against Cancer (AECC), by doctors Isabel Orbe, Nieves Mijimolle, Francesc Cardellach, Albert Biete and Mercedes Fernandez. November 29th, 2016. Place: Aula Magna, Faculty of Medicine, University of Barcelona Dr. Isabel Orbe, Director of the Scientific...
Amazing conferences on the most recent breakthroughs in cancer and new collaborations with world-leading experts!! This B-Debate, organized by IRB Barcelona scientists Raúl Méndez, Salvador Aznar-Benitah and Eduard Batlle, with Biocat and "la Caixa" Foundation, has gathered international experts in the fields of RNA processing and...
Excellent Barcelona BioMed Conference! (October 3-5, 2016) Many features of the development and physiology of living organisms are made possible by the plasticity of epithelial cells. Not only does it enable their transformation to different cell types, which is often reversible, it also facilitates their migration to...
Launch of a global movement for cancer research. The World Cancer Research Day gives us the opportunity to raise awareness and commit to the progress of cancer research as the only way to restrain the disease and improve patient survival rates and quality of life....
We thank Kimberly Brown (Henry Ford Hospital, Detroit), Bruce Bacon (Saint Louis University), and K. Rajender Reddy (University of Pennsylvania) for the invitation to write this article. "Pathogenesis of portal hypertension: Extrahepatic mechanisms" by Mercedes Fernandez, Marc Mejias, Ester Garcia-Pras, Javier Gallego, Nuria Pell, Marta Ramirez,...
Since our manuscript went on line it's had a bit of press coverage...
Published in Gastroenterology (2016) 150:982-997 "Sequential functions of CPEB1 and CPEB4 regulate pathologic expression of VEGF and angiogenesis in chronic liver disease", by Vittorio Calderone, Javier Gallego, Gonzalo Fernandez-Miranda, Ester Garcia-Pras, Carlos Maillo, Annalisa Berzigotti, Marc Mejias, Felice Alessio Bava, Ana Angulo-Urarte, Mariona Graupera, Pilar Navarro, Jaime...
We gratefully appreciate their support!...